Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29862857 | 1.00 | AKT1 (0.36) | AKT1SCN9ACYP17A1ATRGSK3B | |
| SCHEMBL24427691 | 0.85 | RXFP1 (0.35) | AKT1SCN9ACYP17A1ATRGSK3B | |
| SCHEMBL15060517 | 0.84 | ATR (0.39) | SCN9ACYP17A1ATRGSK3BDYRK1A | |
| SCHEMBL19205217 | 0.84 | ATR (0.39) | SCN9ACYP17A1ATRGSK3BDYRK1A | |
| SCHEMBL38661717 | 0.83 | ATR (0.49) | SCN9ACYP17A1ATRGSK3BDYRK1A | |
| SCHEMBL38663529 | 0.83 | ATR (0.49) | SCN9ACYP17A1ATRGSK3BDYRK1A | |
| SCHEMBL18153003 | 0.81 | MAPK8 (0.42) | SCN9AMAPK14 | |
| SCHEMBL24427294 | 0.81 | PRMT1 (0.38) | SCN9ACYP17A1ATRGSK3BDYRK1A | |
| SCHEMBL24726041 | 0.80 | KCNQ3 (0.38) | SCN9ACYP17A1ATRGSK3BDYRK1A | |
| SCHEMBL29862959 | 0.80 | KCNQ3 (0.38) | SCN9ACYP17A1ATRGSK3BDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998263-A1 | TRICYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Jemincare Pharmaceuticals Co., Ltd. (CN) | 2022-05-18 | — | — | EP | disclosed |