Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 20/20 | 0.67 |
| ▸ | HTR2B | P41595 | 2/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2432029 | 0.81 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2435850 | 0.76 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2433938 | 0.76 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2432115 | 0.67 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2438642 | 0.67 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2440111 | 0.65 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2436208 | 0.65 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2437701 | 0.64 | GHSR (1.00) | GHSRHTR2BKCNH2 | |
| SCHEMBL2435431 | 0.63 | GHSR (0.78) | GHSRHTR2BKCNH2 | |
| SCHEMBL2435480 | 0.63 | GHSR (0.78) | GHSRHTR2BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230461-A1 | 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES | PFIZER INC. | 2011-09-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230461-A1 | 2,3-DIHYDRO-1H-INDEN-1-YL-2,7-DIAZASPIRO[3.5] NONANE DERIVATIVES | GIPR, GLP1R, GHSR | GHSR 3/4885HTR2B 366/4885KCNH2 984/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.