Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 2/20 | 0.59 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6543956 | 1.00 | FBP1 (0.59) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL19244366 | 0.88 | TTR (0.55) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL19244365 | 0.88 | TTR (0.55) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL6543092 | 0.87 | FBP1 (0.57) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL2435547 | 0.87 | FBP1 (0.57) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL1879100 | 0.82 | TTR (0.57) | TTRDPP4KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1895095 | 0.82 | MAPT (0.53) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL1895094 | 0.82 | MAPT (0.53) | FBP1TTRDPP4KDM4EALDH1A1 | |
| SCHEMBL21188478 | 0.80 | CYP3A4 (0.46) | FBP1TTRDPP4PPARAPPARG | |
| SCHEMBL19244446 | 0.79 | KDM4E (0.47) | FBP1KDM4EALDH1A1SMN1; SMN2MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |
| EP-1433786-A1 | Benzoxazole compound and pharmaceutical composition containing the compound | Kowa Company Ltd. (JP) | 2004-06-30 | — | — | EP | disclosed |