Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CAMKK1 | Q8N5S9 | 2/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30822046 | 0.98 | PTGDR2 (0.47) | PTGDR2NPC1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL2446791 | 0.98 | PTGDR2 (0.47) | PTGDR2NPC1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL1515853 | 0.98 | PTGDR2 (0.47) | PTGDR2NPC1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL17681983 | 0.96 | CYP2D6 (0.43) | PTGDR2NPC1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL29932760 | 0.92 | NOTUM (0.42) | NPC1RAB9AHCRTR1HCRTR2KMT2A | |
| SCHEMBL16025390 | 0.92 | NOTUM (0.42) | NPC1RAB9AHCRTR1HCRTR2KMT2A | |
| SCHEMBL8384797 | 0.85 | KDM4E (0.39) | NPC1RAB9AHCRTR1HCRTR2KMT2A | |
| SCHEMBL4742961 | 0.84 | PTGDR2 (0.47) | PTGDR2NPC1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL27614351 | 0.84 | PTGDR2 (0.38) | PTGDR2NPC1RAB9ACYP2D6SLC6A2 | |
| SCHEMBL18197670 | 0.84 | KAT2B (0.43) | GAAMAPTALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |
| US-5936128-A | BENZENETHIOL COMPOUNDS AS INTERMEDIATES; BACTERICIDES, VIRICIDES; HIV | WARNER-LAMBERT COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| EP-0729464-A1 | 5,6-DIHYDROPYRONE DERIVATIVES AS PROTEASE INHIBITORS AND ANTIVIRAL AGENTS | PARKE, DAVIS & COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |