Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1515853 | 1.00 | PTGDR2 (0.47) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| SCHEMBL30822046 | 1.00 | PTGDR2 (0.47) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| SCHEMBL2442839 | 0.98 | PTGDR2 (0.45) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| SCHEMBL17681983 | 0.94 | CYP2D6 (0.43) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| SCHEMBL29932760 | 0.90 | NOTUM (0.42) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL16025390 | 0.90 | NOTUM (0.42) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL27614351 | 0.85 | PTGDR2 (0.38) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| SCHEMBL341578 | 0.85 | PTGDR2 (0.50) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| SCHEMBL28794360 | 0.85 | PTGDR2 (0.50) | PTGDR2NPC1RAB9APTGS2CYP2D6 | |
| 2-Aminoacetophenone SCHEMBL8641865 | 0.84 | HDAC3 (0.44) | PTGDR2NPC1RAB9APTGS2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362765-A2 | PERFUME SYSTEMS | The Procter & Gamble Company (US) | 2011-09-07 | — | — | EP | claimed |
| WO-2010065446-A2 | PERFUME SYSTEMS | THE PROCTER & GAMBLE COMPANY (US) | 2010-06-10 | — | — | WO | claimed |