SCHEMBL24428627

SCHEMBL24428627

Cc1cccc(-c2coc3ccccc23)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
KDM4E B2RXH2 1/20 0.39
USP2 O75604 1/20 0.39
HPGD P15428 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MAOB P27338 4/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
GSK3B P49841 4/20 0.35
KCNA3 P22001 2/20 0.35
CDK2 P24941 2/20 0.35
CYP2A6 P11509 2/20 0.34
CYP1A2 P05177 1/20 0.34
MAOA P21397 1/20 0.34
FTO Q9C0B1 1/20 0.34
MIF P14174 1/20 0.34
CHRNB2 P17787 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22923731 0.83 NOTUM (0.41) MAOBCHRM2CHRM4CHRM5CHRM1
SCHEMBL1133152 0.79 CHRM2 (0.41) ALDH1A1KDM4EUSP2HPGDHSD17B10
SCHEMBL2490828 0.78 CHRM2 (0.50) ALDH1A1KDM4EHPGDHSD17B10MAOB
SCHEMBL20777154 0.75 AHR (0.42) ALDH1A1KDM4EUSP2HPGDHSD17B10
SCHEMBL10715263 0.75 CYP2A6 (0.43) ALDH1A1CYP2A6CYP1A2
SCHEMBL22923653 0.74 CHRM2 (0.33) MAOBCHRM2CHRM4CHRM5CHRM1
SCHEMBL16934082 0.73 TSHR (0.43) ALDH1A1HPGDHSD17B10CYP2A6CYP1A2
SCHEMBL23661621 0.73 CHRM2 (0.37) MAOBCHRM2CHRM4CHRM5CHRM1
SCHEMBL11442831 0.73 ALDH1A1 (0.42) ALDH1A1KDM4EHPGDHSD17B10MAOB
SCHEMBL13268057 0.72 KDM4E (0.68) ALDH1A1KDM4EUSP2HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3998321-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE SFC Co., Ltd. (KR) 2022-05-18 EP disclosed