SCHEMBL24428634

SCHEMBL24428634

Cc1coc2ccc(N(c3ccccc3)c3ccccc3)cc12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 4/20 0.38
ALDH1A1 P00352 9/20 0.37
KDM4E B2RXH2 4/20 0.37
POLB P06746 3/20 0.37
HPGD P15428 2/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
MAPT P10636 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PFKFB3 Q16875 2/20 0.35
RAB9A P51151 2/20 0.33
TSHR P16473 2/20 0.33
MAOB P27338 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KMT2A Q03164 2/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19685691 0.88 ALDH1A1 (0.41) ALDH1A1KDM4EHPGDCYP1A2CYP3A4
SCHEMBL24758020 0.80 ALDH1A1 (0.37) ALDH1A1KDM4EL3MBTL1CYP1A2CYP3A4
SCHEMBL19686110 0.80 ALDH1A1 (0.38) KCNA3ALDH1A1KDM4EPOLBHPGD
SCHEMBL19685799 0.80 ALDH1A1 (0.35) KCNA3ALDH1A1KDM4EPOLBHPGD
SCHEMBL24758876 0.80 ALDH1A1 (0.34) ALDH1A1KDM4EPOLBL3MBTL1CYP1A2
SCHEMBL22312247 0.79 EGFR (0.41) KCNA3ALDH1A1KDM4EHPGDMAPT
SCHEMBL19685679 0.78 ALDH1A1 (0.45) KCNA3ALDH1A1KDM4EPOLBHPGD
SCHEMBL19685687 0.78 PTPN1 (0.52) ALDH1A1CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL24326238 0.75 KDM4E (0.40) ALDH1A1KDM4EPOLBHPGDL3MBTL1
SCHEMBL18927789 0.74 ALDH1A1 (0.45) ALDH1A1KDM4EPOLBHPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3998321-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE SFC Co., Ltd. (KR) 2022-05-18 EP disclosed