SCHEMBL24428677

SCHEMBL24428677

Cc1c2ccccc2c(-c2ccc3c(c2)oc2c(-c4ccc5c(c4)-c4ccccc4C5(C)C)cccc23)c2ccccc12

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.42
PRKDC P78527 1/20 0.39
GGPS1 O95749 1/20 0.35
PGR P06401 1/20 0.32
PTGES2 Q9H7Z7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22947415 0.92 ALOX5 (0.43) ALOX5PRKDCGGPS1PGRPTGES2
SCHEMBL22915696 0.89 ALOX5 (0.40) ALOX5PRKDCGGPS1PTGES2
SCHEMBL25493502 0.86 ALOX5 (0.36) ALOX5PRKDCGGPS1
SCHEMBL22947313 0.86 ALOX5 (0.38) ALOX5PRKDCGGPS1PGR
SCHEMBL24285538 0.85 ALOX5 (0.46) ALOX5PRKDCGGPS1PGRPTGES2
SCHEMBL17944715 0.84 PRKDC (0.36) PRKDC
SCHEMBL17944560 0.84 ALOX5 (0.42) ALOX5PRKDCGGPS1PGRPTGES2
SCHEMBL24130692 0.84 MEN1 (0.41) ALOX5PRKDCPGR
SCHEMBL22706480 0.83 ALOX5 (0.39) ALOX5PRKDCPGR
SCHEMBL22706481 0.83 ALOX5 (0.47) ALOX5PRKDCGGPS1PGRPTGES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3998321-A1 ORGANIC LIGHT EMITTING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE SFC Co., Ltd. (KR) 2022-05-18 EP disclosed