SCHEMBL24428883

SCHEMBL24428883

O=c1c2ccc3c4c(ccc(c24)c2cc4ccccc4n12)c(=O)n1c2ccccc2cc31

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.45
KMT2A Q03164 4/20 0.42
CASP1 P29466 2/20 0.42
CASP7 P55210 2/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
GALK1 P51570 1/20 0.42
BLM P54132 1/20 0.42
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
DAO P14920 2/20 0.40
BCL2 P10415 1/20 0.38
CYP1A2 P05177 3/20 0.37
CAMKK1 Q8N5S9 2/20 0.37
CAMKK2 Q96RR4 2/20 0.37
CYP2C9 P11712 2/20 0.37
CYP2C19 P33261 2/20 0.37
MEN1 O00255 2/20 0.37
MAPT P10636 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17856833 0.89 AHR (0.47) CDC25BKMT2ACASP1CASP7HSD17B10
SCHEMBL13148862 0.87 PARP1 (0.40) CDC25BKMT2ACASP1CASP7HSD17B10
SCHEMBL18877313 0.84 BCL2 (0.57) KMT2ACASP1CASP7HSD17B10GAA
SCHEMBL18877309 0.84 BCL2 (0.57) KMT2ACASP1CASP7HSD17B10GAA
SCHEMBL18877312 0.84 BCL2 (0.57) KMT2ACASP1CASP7HSD17B10GAA
SCHEMBL17518046 0.82 KMT2A (0.43) CDC25BKMT2ACASP1CASP7HSD17B10
SCHEMBL38660783 0.80 DAO (0.47) CDC25BKMT2ACASP1CASP7HSD17B10
SCHEMBL12324447 0.79 GAA (0.51) CDC25BKMT2ACASP1CASP7HSD17B10
SCHEMBL17794403 0.79 HPGD (0.39) CDC25BKMT2ACASP1CASP7HSD17B10
SCHEMBL17794402 0.79 HPGD (0.39) CDC25BKMT2ACASP1CASP7HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3605629-B1 ORGANIC SEMICONDUCTOR ELEMENT, ORGANIC SEMICONDUCTOR COMPOSITION, ORGANIC SEMICONDUCTOR FILM PRODUCTION METHOD, ORGANIC SEMICONDUCTOR FILM, AND COMPOUND AND POLYMER USED THEREFOR FUJIFILM CORP (JP) 2022-05-18 EP disclosed