Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 2/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | GALK1 | P51570 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17794403 | 1.00 | HPGD (0.39) | HPGDKMT2ACASP1CASP7GAA | |
| SCHEMBL19598983 | 0.89 | KDM4E (0.41) | HPGDKMT2ACASP1CASP7GAA | |
| SCHEMBL17785100 | 0.87 | AHR (0.45) | HPGDKMT2ACASP1CASP7GAA | |
| SCHEMBL19598994 | 0.79 | ALDH1A1 (0.36) | HPGDKMT2AGAAPKMHSD17B10 | |
| SCHEMBL19598966 | 0.79 | ALDH1A1 (0.36) | HPGDKMT2AGAAPKMHSD17B10 | |
| SCHEMBL19598965 | 0.79 | ALDH1A1 (0.36) | HPGDKMT2AGAAPKMHSD17B10 | |
| SCHEMBL19598995 | 0.79 | ALDH1A1 (0.36) | HPGDKMT2AGAAPKMHSD17B10 | |
| SCHEMBL24428883 | 0.79 | CDC25B (0.45) | HPGDKMT2ACASP1CASP7GAA | |
| SCHEMBL19598984 | 0.77 | IDO1 (0.38) | HPGDKMT2ACASP1CASP7GAA | |
| SCHEMBL19598967 | 0.77 | ALDH1A1 (0.37) | HPGDKMT2AGAAPKMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3224246-B1 | 4-OXOQUINOLINE COMPOUNDS | BASF SE (DE) | 2022-01-12 | — | — | EP | disclosed |
| US-20170331049-A1 | 4-OXOQUINOLINE COMPOUNDS | BASF SE (DE) | 2017-11-16 | — | — | US | disclosed |
| US-20170331049-A1 | 4-OXOQUINOLINE COMPOUNDS | BASF SE (DE) | 2017-11-16 | — | — | US | disclosed |
| WO-2016083914-A1 | 4-OXOQUINOLINE COMPOUNDS | BASF SE (DE) | 2016-06-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170331049-A1 | 4-OXOQUINOLINE COMPOUNDS | DRD4, PRMT7, PRMT8 | HPGD 4109/4885KMT2A 905/4885CASP1 1042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.