SCHEMBL24433094

SCHEMBL24433094

Cc1c(O)cc(O)c2c1OC(c1ccc(O)c(O)c1)C(O)C2=O

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SYNJ2 O15056 3/20 0.67
RECQL P46063 2/20 0.61
SOST Q9BQB4 2/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
KDM4E B2RXH2 1/20 0.61
POLB P06746 1/20 0.61
GAA P10253 1/20 0.61
MAPT P10636 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
ALOX15 P16050 1/20 0.61
ALOX12 P18054 1/20 0.61
NFKB1 P19838 1/20 0.61
MAPK1 P28482 1/20 0.61
HIF1A Q16665 1/20 0.61
HSD17B10 Q99714 1/20 0.61
IDO1 P14902 1/20 0.54
NSD2 O96028 1/20 0.54
TDO2 P48775 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29574970 1.00 SYNJ2 (0.67) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL24433090 1.00 SYNJ2 (0.67) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL5073942 0.88 RECQL (0.65) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL3191589 0.88 RECQL (0.65) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL31162504 0.88 RECQL (0.65) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL17157085 0.81 SYNJ2 (1.00) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL24433093 0.81 SYNJ2 (1.00) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL18517028 0.81 SYNJ2 (1.00) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL15773442 0.81 SYNJ2 (1.00) SYNJ2RECQLSOSTMEN1KMT2A
SCHEMBL30190408 0.77 RECQL (0.56) SYNJ2RECQLSOSTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220151274-A1 PREPARATIONS WITH C-METHYL FLAVONOIDS ANALYTICON DISCOVERY GMBH (DE) 2022-05-19 US disclosed