Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP2 | P42575 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24433547 | 0.97 | TSHR (0.47) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL23334540 | 0.93 | TSHR (0.51) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL26375472 | 0.93 | MEN1 (0.47) | TSHRALDH1A1HPGDLMNAPKM | |
| SCHEMBL19155468 | 0.92 | TSHR (0.50) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25649009 | 0.89 | TSHR (0.50) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL23334520 | 0.88 | FAAH (0.50) | TSHRCNR1CASP2GLP1R | |
| SCHEMBL25978308 | 0.87 | TSHR (0.51) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL17486533 | 0.86 | TSHR (0.49) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20857449 | 0.86 | TSHR (0.41) | TSHRALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL13616087 | 0.86 | MEN1 (0.53) | TSHRALDH1A1HPGDLMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220152231-A1 | PROCESS OF PREPARING POLYMERIC NANOPARTICLES THAT CHELATE RADIOACTIVE ISOTOPES AND HAVE A SURFACE MODIFIED WITH SPECIFIC MOLECULES TARGETING THE PSMA RECEPTOR AND THEIR USE | NANOTHEA S.A. (PL) | 2022-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220152231-A1 | PROCESS OF PREPARING POLYMERIC NANOPARTICLES THAT CHELATE RADIOACTIVE ISOTOPES AND HAVE A SURFACE MODIFIED WITH SPECIFIC MOLECULES TARGETING THE PSMA RECEPTOR AND THEIR USE | PSMA1, PSMA2, PSMA3 | TSHR 1652/4885ALDH1A1 224/4885HPGD 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.