⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868731 | 0.81 | HRH4 (0.33) | — | |
| SCHEMBL24433774 | 0.79 | — | — | |
| SCHEMBL24433783 | 0.79 | CAPN1 (0.31) | — | |
| SCHEMBL14868636 | 0.74 | — | — | |
| SCHEMBL14868730 | 0.74 | — | — | |
| SCHEMBL14868732 | 0.72 | — | — | |
| SCHEMBL19164773 | 0.72 | — | — | |
| SCHEMBL14868735 | 0.72 | ALOX5 (0.35) | — | |
| SCHEMBL14868697 | 0.72 | — | — | |
| SCHEMBL14868725 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11759441-B2 | Biguanide compositions and methods of treating metabolic disorders | ANJI PHARMACEUTICALS INC. (US) | 2023-09-19 | — | — | US | disclosed |
| US-20220151957-A1 | BIGUANIDE COMPOSITIONS AND METHODS OF TREATING METABOLIC DISORDERS | ANJI PHARMACEUTICALS INC. | 2022-05-19 | — | — | US | disclosed |