SCHEMBL24434436

SCHEMBL24434436

C[C@@H]1CC(=O)C=C2CCC(C(=O)O)C[C@]21C

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.73
ALDH1A1 P00352 7/20 0.38
SHBG P04278 7/20 0.38
SMN1; SMN2 Q16637 6/20 0.38
LMNA P02545 5/20 0.38
MAPK1 P28482 5/20 0.38
CYP3A4 P08684 4/20 0.38
SERPINA6 P08185 4/20 0.38
MAPT P10636 3/20 0.38
TSHR P16473 3/20 0.38
NR3C1 P04150 3/20 0.38
PMP22 Q01453 3/20 0.38
NPSR1 Q6W5P4 3/20 0.38
CYP2C9 P11712 2/20 0.38
HIF1A Q16665 2/20 0.38
ABCB11 O95342 2/20 0.38
PGR P06401 2/20 0.38
ADRA1A P35348 2/20 0.38
HTR2B P41595 2/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6857288 0.89 CYP2C19 (0.78) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
SCHEMBL16188788 0.89 CYP2C19 (0.78) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
Nootkatone SCHEMBL14137791 0.84 CYP2C19 (1.00) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
Nootkatone SCHEMBL309679 0.84 CYP2C19 (1.00) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
Nootkatone SCHEMBL10146951 0.84 CYP2C19 (1.00) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
Nootkatone SCHEMBL110855 0.84 CYP2C19 (1.00) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
Nootkatone SCHEMBL335639 0.84 CYP2C19 (1.00) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
Nootkatone SCHEMBL3276192 0.84 CYP2C19 (1.00) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
SCHEMBL15462827 0.76 CYP2C19 (0.60) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA
SCHEMBL20671327 0.75 CYP2C19 (0.59) CYP2C19ALDH1A1SHBGSMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220154113-A1 EXPRESSION OF HETEROLOGOUS ENZYMES IN YEAST FOR FLAVOURED ALCOHOLIC BEVERAGE PRODUCTION DANSTAR FERMENT AG (CH) 2022-05-19 US disclosed