Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.43 |
| ▸ | SHBG | P04278 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16188788 | 1.00 | CYP2C19 (0.78) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| SCHEMBL24434436 | 0.89 | CYP2C19 (0.73) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| Nootkatone SCHEMBL14137791 | 0.87 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| Nootkatone SCHEMBL309679 | 0.87 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| Nootkatone SCHEMBL335639 | 0.87 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| Nootkatone SCHEMBL110855 | 0.87 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| Nootkatone SCHEMBL10146951 | 0.87 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| Nootkatone SCHEMBL3276192 | 0.87 | CYP2C19 (1.00) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| 11,12-Epoxynootkatone SCHEMBL13588488 | 0.76 | CYP2C19 (0.60) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 | |
| SCHEMBL15462827 | 0.76 | CYP2C19 (0.60) | CYP2C19SMN1; SMN2CYP3A4LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6787671-B2 | FOR PRODUCTION OF ALDEHYDES, CARBOXYLIC ACIDS, ESTERS, OR KETONES VIA REACTION OF OSMIUM CATALYST AND PEROXYMONOSULFURIC ACID | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2004-09-07 | — | — | US | disclosed |
| US-20030149299-A1 | Catalytic osmium-assisted oxidative cleavage of olefins | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY | 2003-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030149299-A1 | Catalytic osmium-assisted oxidative cleavage of olefins | OXER1, OXSR1, AOX1 | CYP2C19 1035/4885SMN1; SMN2 3725/4885CYP3A4 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.