Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736687 | 0.84 | — | — | |
| SCHEMBL94221 | 0.82 | POLB (0.42) | POLBGAAMAPTTSHRALDH1A1 | |
| SCHEMBL8723746 | 0.79 | — | — | |
| SCHEMBL7780750 | 0.75 | — | — | |
| SCHEMBL8283932 | 0.74 | POLB (0.34) | POLBGAAMAPT | |
| Alcohol SCHEMBL2594726 | 0.74 | GAA (0.43) | POLBGAAMAPTTSHRALDH1A1 | |
| SCHEMBL14071570 | 0.72 | POLB (0.38) | POLBGAAMAPTTSHRALDH1A1 | |
| SCHEMBL30740684 | 0.71 | GAA (0.36) | POLBGAAMAPTTSHR | |
| SCHEMBL2742898 | 0.70 | MAPT (0.41) | POLBGAAMAPTTSHRALDH1A1 | |
| SCHEMBL14235866 | 0.70 | ALDH1A1 (0.38) | MAPTTSHRALDH1A1MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283754-B | Squaraine compound and derivative targeting PSMA and application thereof | 北京师范大学 | 2024-10-15 | — | — | CN | disclosed |
| CN-116283754-A | Squaraine compound and derivative targeting PSMA and application thereof | 北京师范大学 | 2023-06-23 | — | — | CN | disclosed |
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| EP-2371421-A1 | Ligands of insulin degrading enzyme and their uses | Université de Lille 2 Droit et Santé (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011107948-A2 | LIGANDS OF INSULIN DEGRADING ENZYME AND THEIR USES | UNIVERSITE LILLE 2 DROIT ET SANTE (FR) | 2011-09-09 | — | — | WO | disclosed |