Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397871 | 0.85 | EP300 (0.47) | HMGCRHTTMAOBTUBB1TP53 | |
| SCHEMBL21614404 | 0.82 | CYP3A4 (0.46) | HMGCRHTTMAOBTUBB1TP53 | |
| SCHEMBL21614371 | 0.80 | HMGCR (0.41) | HMGCRHTTMAOBTUBB1TP53 | |
| SCHEMBL21614377 | 0.80 | ESR1 (0.42) | HMGCRHTTMAOBTUBB1TP53 | |
| SCHEMBL21614373 | 0.80 | HMGCR (0.41) | HMGCRHTTMAOBTUBB1TP53 | |
| SCHEMBL24445888 | 0.79 | MAOB (0.40) | HMGCRHTTMAOBTUBB1TP53 | |
| SCHEMBL3623027 | 0.77 | ACHE (0.48) | HMGCRMAOBTUBB1TP53CYP3A4 | |
| SCHEMBL4403305 | 0.77 | HMGCR (0.43) | HMGCRHTTMAOBTUBB1CYP3A4 | |
| SCHEMBL714254 | 0.76 | MAOB (0.46) | HTTMAOBTUBB1TP53CYP3A4 | |
| SCHEMBL21614374 | 0.76 | HMGCR (0.41) | HMGCRHTTMAOBTUBB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220157484-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2022-05-19 | — | — | US | disclosed |