SCHEMBL24436699

SCHEMBL24436699

CC(=O)Oc1c(O)cccc1F

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.45
HSD17B10 Q99714 2/20 0.45
TP53 P04637 1/20 0.45
GAA P10253 1/20 0.45
MAPT P10636 1/20 0.45
HTT P42858 1/20 0.45
MAPK1 P28482 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
CYP3A4 P08684 1/20 0.43
THRB P10828 1/20 0.42
PREP P48147 2/20 0.41
KMT2A Q03164 2/20 0.41
CELA1 Q9UNI1 1/20 0.41
SLC2A1 P11166 1/20 0.41
SLC2A4 P14672 1/20 0.41
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA12 O43570 1/20 0.39
CA7 P43166 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1994318 0.88 KMT2A (0.49) KDM4EHSD17B10TP53GAAMAPT
SCHEMBL7093557 0.86 KDM4E (0.52) KDM4EHSD17B10TP53GAAMAPT
SCHEMBL14181682 0.81 KDM4E (0.61) KDM4EHSD17B10TP53GAAMAPT
SCHEMBL6060769 0.80 CA1 (0.41) HSD17B10MAPTHTTMAPK1ALDH1A1
SCHEMBL4748927 0.79 GAA (0.42) KDM4EHSD17B10GAAMAPTMAPK1
SCHEMBL28440932 0.79 KDM4E (0.42) KDM4EHSD17B10TP53GAAMAPT
SCHEMBL10808312 0.78 MAPK1 (0.62) KDM4EHSD17B10TP53GAAMAPT
SCHEMBL2047863 0.78 KDM4E (0.62) KDM4EHSD17B10TP53GAAMAPT
SCHEMBL10435321 0.78 KDM4E (0.41) KDM4EHSD17B10MAPK1ALDH1A1HPGD
SCHEMBL6442740 0.78 KDM4E (0.67) KDM4EHSD17B10MAPK1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed
US-20220157484-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-19 US disclosed