SCHEMBL4748927

SCHEMBL4748927

CC(=O)Oc1c(F)cccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GAA P10253 7/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 2/20 0.42
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
TAS1R2 Q8TE23 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 1/20 0.39
ABCB11 O95342 1/20 0.39
LPAR1 Q92633 1/20 0.39
LPAR5 Q9H1C0 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1994318 0.86 KMT2A (0.49) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL3006462 0.86 KDM4E (0.48) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL9326165 0.84 KDM4E (0.47) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL27352499 0.81 KMT2A (0.42) GAAKDM4EKMT2ATAS1R3TAS1R1
SCHEMBL7508588 0.81 SMN1; SMN2 (0.43) KDM4EALDH1A1HPGDKMT2ASMN1; SMN2
SCHEMBL6937651 0.79 MAPK1 (0.61) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL9501805 0.79 KDM4E (0.61) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL24436699 0.79 KDM4E (0.45) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL14181682 0.79 KDM4E (0.61) GAAMAPK1KDM4EALDH1A1HPGD
SCHEMBL3383096 0.79 ALDH1A1 (0.53) GAAMAPK1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10483466-B2 P-doping cross-linking of organic hole transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US claimed
EP-3114715-B1 P-DOPING CROSS-LINKING OF ORGANIC HOLE TRANSPORTERS SIEMENS AG (DE) 2019-10-30 EP claimed
US-20180198069-A1 P-Doping Cross-Linking Of Organic Hole Transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2018-07-12 US claimed
CN-114984003-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2024-08-27 CN disclosed
CN-115054600-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2024-06-14 CN disclosed
CN-115054600-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-16 CN disclosed
CN-114984003-A Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-09-02 CN disclosed
CN-109415321-B Aromatic sulfonamide derivatives 拜耳制药股份公司 2022-06-17 CN disclosed
US-10483466-B2 P-doping cross-linking of organic hole transporters SIEMENS AKTIENGESELLSCHAFT (DE) 2019-11-19 US disclosed
CN-106459744-B Double-core main group metal phosphorescent emitters 西门子公司 2019-08-30 CN disclosed
CN-106459746-B Sequential functionalization of phosphorescent emitter layers 西门子公司 2019-08-02 CN disclosed
EP-0885610-A1 TRACHEAL SMOOTH MUSCLE RELAXANT NIPPON SUISAN KAISHA, LTD. (JP) 1998-12-23 EP disclosed
US-5734067-A THERAPY FOR CANCER, ARTHEROSCLEROSIS OR LIVER DISEASES NIPPON SUISAN KAISHA, LTD. (JP) 1998-03-31 US disclosed
EP-0805155-A1 NOVEL ANTIOXIDANT TRICYCLIC FUSED HETEROCYCLIC COMPOUND NIPPON SUISAN KAISHA, LTD. (JP) 1997-11-05 EP disclosed
CN-1033031-C Modified gangliosides and functional derivatives thereof FIDIA SPA (IT) 1996-10-16 CN disclosed
EP-0630921-A2 Functional polymers and their production NIPPON PAINT CO., LTD. (JP) 1994-12-28 EP disclosed
US-5238947-A Antitumor agents UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1993-08-24 US disclosed
WO-1991016309-A1 SYNTHETIC PIPERIDINEDIONES WITH CYTOSTATIC ACTIVITY UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1991-10-31 WO disclosed
CN-1051912-A Improved gangliosides and functional derivatives thereof FIDIA B P A (IT) 1991-06-05 CN disclosed
EP-0207621-A2 Functional polymers and their production Nippon Paint Co., Ltd. (JP) 1987-01-07 EP disclosed