Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | FOXM1 | Q08050 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24437971 | 0.95 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL21842123 | 0.82 | SMN1; SMN2 (0.54) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL21842364 | 0.82 | SMN1; SMN2 (0.54) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL21842124 | 0.82 | SMN1; SMN2 (0.54) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7777018 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL3679901 | 0.81 | ALDH1A1 (0.52) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL24437848 | 0.79 | CYP1A2 (0.57) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL7776906 | 0.78 | ALDH1A1 (0.53) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL22759948 | 0.78 | CYP1A2 (0.56) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL18677293 | 0.78 | SMN1; SMN2 (0.48) | KDM4EALDH1A1SMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022101453-A1 | COMPOUNDS AND METHODS FOR TREATING A CYTOKINE-MEDIATED DISEASE | Conservatoire National des Arts et Métiers (FR) | 2022-05-19 | — | — | WO | disclosed |