Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439344 | 0.91 | SLCO1B1 (0.48) | SLCO1B1NPC1LMNANPSR1FFAR4 | |
| SCHEMBL29672297 | 0.91 | SLCO1B1 (0.48) | SLCO1B1NPC1LMNANPSR1FFAR4 | |
| SCHEMBL29672263 | 0.91 | SLCO1B1 (0.48) | SLCO1B1NPC1LMNANPSR1FFAR4 | |
| SCHEMBL29517757 | 0.90 | SLCO1B1 (0.40) | SLCO1B1NPC1LMNANPSR1FFAR4 | |
| SCHEMBL24439720 | 0.90 | SLCO1B1 (0.40) | SLCO1B1NPC1LMNANPSR1FFAR4 | |
| SCHEMBL24439627 | 0.82 | MEN1 (0.36) | SLCO1B1NPC1LMNANPSR1ALDH1A1 | |
| SCHEMBL24439631 | 0.82 | SLCO1B1 (0.40) | SLCO1B1NPC1LMNANPSR1FFAR4 | |
| SCHEMBL29672278 | 0.80 | CSNK2A1 (0.36) | FFAR4SCN9AUGCGKMOPDE4D | |
| SCHEMBL24439721 | 0.80 | CSNK2A1 (0.36) | FFAR4SCN9AUGCGKMOPDE4D | |
| SCHEMBL24439407 | 0.78 | SLCO1B1 (0.59) | SLCO1B1NPC1FFAR4SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |