Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439608 | 0.83 | NPC1 (0.43) | MEN1KMT2ARAB9AALDH1A1SLCO1B1 | |
| SCHEMBL24439407 | 0.82 | SLCO1B1 (0.59) | MEN1KMT2ARAB9ASLCO1B1NPC1 | |
| SCHEMBL24439348 | 0.82 | SLCO1B1 (0.36) | MEN1KMT2ARAB9AALDH1A1SLCO1B1 | |
| SCHEMBL24439624 | 0.81 | SLCO1B1 (0.50) | MEN1KMT2ARAB9ASLCO1B1NPC1 | |
| SCHEMBL29672297 | 0.77 | SLCO1B1 (0.48) | SLCO1B1NPC1NPSR1LMNA | |
| SCHEMBL29672263 | 0.77 | SLCO1B1 (0.48) | SLCO1B1NPC1NPSR1LMNA | |
| SCHEMBL24439344 | 0.77 | SLCO1B1 (0.48) | SLCO1B1NPC1NPSR1LMNA | |
| SCHEMBL24439720 | 0.76 | SLCO1B1 (0.40) | SLCO1B1NPC1NPSR1LMNA | |
| SCHEMBL29517757 | 0.76 | SLCO1B1 (0.40) | SLCO1B1NPC1NPSR1LMNA | |
| SCHEMBL22256655 | 0.76 | SLCO1B1 (0.40) | MEN1KMT2ARAB9ASLCO1B1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| CN-114456147-A | Oxygen substituted amino carbonate thiophene compounds | 武汉人福创新药物研发中心有限公司 | 2022-05-10 | — | — | CN | disclosed |