Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 8/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.43 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | UBE2N | P61088 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439483 | 0.94 | SLCO1B1 (0.38) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL29517335 | 0.94 | SLCO1B1 (0.38) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439604 | 0.91 | KLKB1 (0.37) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL29672289 | 0.90 | SLCO1B1 (0.52) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL29672239 | 0.90 | SLCO1B1 (0.52) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439408 | 0.90 | SLCO1B1 (0.52) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439488 | 0.90 | SLCO1B1 (0.52) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439318 | 0.89 | SLCO1B1 (0.45) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL24439612 | 0.89 | SLCO1B1 (0.51) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 | |
| SCHEMBL29672276 | 0.89 | SLCO1B1 (0.51) | SLCO1B1LPAR1ABCB11ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |