Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | UBE2N | P61088 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439409 | 0.91 | SLCO1B1 (0.43) | KLKB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24439483 | 0.89 | SLCO1B1 (0.38) | KLKB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL29517335 | 0.89 | SLCO1B1 (0.38) | KLKB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24439388 | 0.88 | SLCO1B1 (0.40) | PDE4APDE4BPDE4CPDE4DACHE | |
| SCHEMBL24439603 | 0.87 | SLCO1B1 (0.41) | PDE4APDE4BPDE4CPDE4DABCC3 | |
| SCHEMBL24439371 | 0.87 | ABCC3 (0.41) | KLKB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24439390 | 0.87 | SLCO1B1 (0.38) | KLKB1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24439319 | 0.87 | SLCO1B1 (0.33) | PDE4APDE4BPDE4CPDE4DABCC3 | |
| SCHEMBL24439489 | 0.86 | SLCO1B1 (0.36) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL24439750 | 0.85 | SLCO1B1 (0.32) | ABCC3ABCC4SLCO1B3SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |