Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24439407 | 0.92 | SLCO1B1 (0.59) | SLCO1B1ABCB11LPAR1NPC1RAB9A | |
| SCHEMBL24439720 | 0.88 | SLCO1B1 (0.40) | SLCO1B1ABCB11LPAR1NPC1FFAR4 | |
| SCHEMBL29517757 | 0.88 | SLCO1B1 (0.40) | SLCO1B1ABCB11LPAR1NPC1FFAR4 | |
| SCHEMBL24439386 | 0.83 | SLCO1B1 (0.43) | SLCO1B1ABCB11LPAR1NPC1RAB9A | |
| SCHEMBL29517791 | 0.81 | SLCO1B1 (0.43) | SLCO1B1ABCB11LPAR1NPC1RAB9A | |
| SCHEMBL24439729 | 0.81 | SLCO1B1 (0.43) | SLCO1B1ABCB11LPAR1NPC1RAB9A | |
| SCHEMBL24439627 | 0.81 | MEN1 (0.36) | SLCO1B1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24439352 | 0.81 | SLCO1B1 (0.40) | SLCO1B1ABCB11LPAR1 | |
| SCHEMBL24439344 | 0.80 | SLCO1B1 (0.48) | SLCO1B1ABCB11LPAR1NPC1FFAR4 | |
| SCHEMBL29672297 | 0.80 | SLCO1B1 (0.48) | SLCO1B1ABCB11LPAR1NPC1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |
| CN-114456147-A | Oxygen substituted amino carbonate thiophene compounds | 武汉人福创新药物研发中心有限公司 | 2022-05-10 | — | — | CN | disclosed |