Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605748 | 1.00 | KDM4E (0.56) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29606907 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29606308 | 0.90 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29605815 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL24439890 | 0.88 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL24439882 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29606360 | 0.87 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL24439700 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL29605177 | 0.86 | ALDH1A1 (0.58) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL24439911 | 0.86 | KDM4E (0.53) | KDM4EALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |