Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLCO1B1 | Q9Y6L6 | 5/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29672269 | 0.91 | SLCO1B1 (0.51) | SLCO1B1ABCB11MEN1KMT2AALDH1A1 | |
| SCHEMBL24439411 | 0.91 | SLCO1B1 (0.51) | SLCO1B1ABCB11MEN1KMT2AALDH1A1 | |
| SCHEMBL29517791 | 0.90 | SLCO1B1 (0.43) | SLCO1B1ABCB11MEN1KMT2ANPC1 | |
| SCHEMBL24439729 | 0.90 | SLCO1B1 (0.43) | SLCO1B1ABCB11MEN1KMT2ANPC1 | |
| SCHEMBL24439631 | 0.86 | SLCO1B1 (0.40) | SLCO1B1ABCB11MEN1KMT2AALDH1A1 | |
| SCHEMBL24439489 | 0.84 | SLCO1B1 (0.36) | SLCO1B1ABCB11MEN1KMT2AALDH1A1 | |
| SCHEMBL29602427 | 0.81 | CNR1 (0.33) | SLCO1B1ABCB11FFAR4S1PR1S1PR3 | |
| SCHEMBL24439682 | 0.81 | CNR1 (0.33) | SLCO1B1ABCB11FFAR4S1PR1S1PR3 | |
| SCHEMBL24441641 | 0.79 | LOX (0.34) | FFAR4 | |
| SCHEMBL24439383 | 0.78 | SLCO1B1 (0.51) | SLCO1B1ABCB11TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022100624-A1 | OXY-SUBSTITUTED AMINOCARBONATE THIOPHENE-BASED COMPOUND AND USE THEREOF | 武汉人福创新药物研发中心有限公司 | 2022-05-19 | — | — | WO | disclosed |