Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | LSS | P48449 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605285 | 1.00 | HPGD (0.59) | HPGDKMT2AADORA2BADORA1L3MBTL1 | |
| SCHEMBL24439763 | 0.91 | GAA (0.59) | HPGDKMT2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL29606877 | 0.91 | GAA (0.59) | HPGDKMT2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL29605252 | 0.90 | MEN1 (0.58) | HPGDKMT2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL24439766 | 0.90 | MEN1 (0.58) | HPGDKMT2AADORA2BADORA1SMN1; SMN2 | |
| SCHEMBL24439764 | 0.89 | POLB (0.54) | HPGDKMT2AADORA2BADORA1POLB | |
| SCHEMBL29605163 | 0.89 | POLB (0.54) | HPGDKMT2AADORA2BADORA1POLB | |
| SCHEMBL24439861 | 0.83 | PSEN1 (0.66) | HPGDKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29606060 | 0.83 | PSEN1 (0.66) | HPGDKMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24439707 | 0.82 | SMN1; SMN2 (0.55) | HPGDKMT2AADORA2BADORA1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |