Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.45 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29605163 | 1.00 | POLB (0.54) | POLBSGMS1ADORA2BADORA1ROCK2 | |
| SCHEMBL24439707 | 0.91 | SMN1; SMN2 (0.55) | POLBSGMS1ADORA2BADORA1ROCK2 | |
| SCHEMBL29605521 | 0.91 | SMN1; SMN2 (0.55) | POLBSGMS1ADORA2BADORA1ROCK2 | |
| SCHEMBL29606877 | 0.89 | GAA (0.59) | SGMS1ADORA2BADORA1THRBHPGD | |
| SCHEMBL24439763 | 0.89 | GAA (0.59) | SGMS1ADORA2BADORA1THRBHPGD | |
| SCHEMBL24439765 | 0.89 | HPGD (0.59) | POLBADORA2BADORA1CYP1A2CYP3A4 | |
| SCHEMBL29605285 | 0.89 | HPGD (0.59) | POLBADORA2BADORA1CYP1A2CYP3A4 | |
| SCHEMBL24439854 | 0.83 | SRC (0.60) | POLBROCK2HPGDKMT2AMAPT | |
| SCHEMBL29604952 | 0.83 | SRC (0.60) | POLBROCK2HPGDKMT2AMAPT | |
| SCHEMBL24439708 | 0.82 | LMNA (0.53) | POLBSGMS1ADORA2BADORA1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103149-A1 | NOVEL CARBAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING SAME AS ACTIVE INGREDIENT | 주식회사 큐라클 | 2022-05-19 | — | — | WO | disclosed |