SCHEMBL244450

SCHEMBL244450

NCCc1cccs1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL28715939 0.98
Hydrochloric Acid SCHEMBL1222329 0.98
Iodide SCHEMBL21835041 0.98
Ethylamine SCHEMBL9874272 0.93 TAAR1 (0.87)
SCHEMBL550841 0.91
Bromide SCHEMBL11232675 0.89 TAAR1 (0.79)
Hydrochloric Acid SCHEMBL1535324 0.89 TAAR1 (0.79)
SCHEMBL921555 0.89 TAAR1 (0.79)
Acetone SCHEMBL9215270 0.88 TAAR1 (0.77)
Carbamic Acid SCHEMBL9213299 0.88 TAAR1 (0.77)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3058 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250387385-A1 TREATMENT FOR GLOMERULAR DISEASES ZYDUS LIFESCIENCES LIMITED (IN) 2025-12-25 US claimed
US-12398277-B2 Dual-modal information storage and anti-counterfeiting material, and its preparation method HANGZHOU NORMAL UNIVERSITY (CN) 2025-08-26 US claimed
EP-4129065-B1 MAMMAL REPELLENT SCENT SCIENCE INT INC (JP) 2025-06-11 EP claimed
EP-4565233-A1 TREATMENT FOR APLASTIC ANEMIA (AA) Zydus Lifesciences Limited (IN) 2025-06-11 EP claimed
CN-120089745-A High-capacity performance silicon-based anode material and preparation method and application thereof 湖南镕锂新材料科技有限公司 2025-06-03 CN claimed
CN-114146441-B Reflux automatic control device and method for intermittent vacuum rectification of high-purity alpha-thiophene derivative 浙江燎原药业有限公司 2025-05-13 CN claimed
EP-4539934-A1 TREATMENT FOR GLOMERULAR DISEASES Zydus Lifesciences Limited (IN) 2025-04-23 EP claimed
CN-119753049-A Preparation method of rotigotine 滁州市庆云医药有限公司 2025-04-04 CN claimed
CN-119638689-A Mizidine thiophene acetamides compound and preparation method and application thereof 盐城工学院 2025-03-18 CN claimed
CN-119584827-A Two-dimensional tin-based perovskite film and preparation method and application thereof 新余学院 2025-03-07 CN claimed
EP-0363869-A1 Substituted thienyl ethyl amines and process for their preparation LONZA AG (CH) 1990-04-18 EP claimed
US-4906756-A 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives SYNTEX (U.S.A.) INC. (US) 1990-03-06 US claimed
EP-0348505-A1 NOVEL N-(1-THIENYLETHYL)AMINE DERIVATIVES AND HERBICIDES CONTAINING THE SAME AS EFFECTIVE INGREDIENT DAIKIN INDUSTRIES, LIMITED (JP) 1990-01-03 EP claimed
EP-0342118-A1 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno (3,2-c)pyridine derivatives ELF SANOFI (FR) 1989-11-15 EP claimed
US-4876362-A Process for the preparation of thienylethylamines SANOFI (FR) 1989-10-24 US claimed
US-4874876-A ACYLATING THIOPHENE, REDUCING, HYDROLYZING OCCIDENTAL CHEMICAL CORPORATION (US) 1989-10-17 US claimed
US-4521584-A USING METAL COMPOUND CATALYST BAYER AKTIENGESELLSCHAFT (DE) 1985-06-04 US claimed
US-4458086-A Process for the preparation of 2-(thienyl-2)-and 2-(thienyl-3)-ethylamines SANOFI (FR) 1984-07-03 US claimed
US-4259231-A ACRYLIC ISOCYANATE CURABLE WITH MOISTURE NITTO ELECTRIC INDUSTRIAL CO., LTD. (JP) 1981-03-31 US claimed
US-4242474-A A POLYHYDROXY ACRYLIC ESTER REACTED WITH AN ISOCYANATE TERMINATED POLYOXYALKYLENE GLYCOL; BIOPOLYMERS TERUMO CORPORATION (JP) 1980-12-30 US claimed