Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.77 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.53 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.53 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.45 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL28972096 | 0.91 | TAAR1 (0.74) | TAAR1POLBADRA2AADRA2BADRA2C | |
| Acetone SCHEMBL9215270 | 0.89 | TAAR1 (0.77) | TAAR1POLBADRA2AADRA2BADRA2C | |
| SCHEMBL244450 | 0.88 | — | — | |
| Iodide SCHEMBL21835041 | 0.86 | — | — | |
| Bromide SCHEMBL28715939 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL1222329 | 0.86 | — | — | |
| Oxalic Acid SCHEMBL1535383 | 0.85 | TAAR1 (0.66) | TAAR1POLBADRA2AADRA2BADRA2C | |
| Acetic Acid Methyl Ester SCHEMBL31318381 | 0.82 | TAAR1 (0.67) | TAAR1POLBADRA2AADRA2BADRA2C | |
| Ethylamine SCHEMBL9874272 | 0.82 | TAAR1 (0.87) | TAAR1POLBADRA2AADRA2BADRA2C | |
| Acetic Acid Methyl Ester SCHEMBL31318382 | 0.81 | TAAR1 (0.65) | TAAR1POLBADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439404-B1 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI SA (FR) | 1995-10-25 | — | — | EP | claimed |
| EP-0439404-A2 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI (FR) | 1991-07-31 | — | — | EP | claimed |
| EP-0439404-B1 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI SA (FR) | 1995-10-25 | — | — | EP | disclosed |
| US-5191090-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno[3,2-c]pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5068360-A | Preparation of 2-(2'-thienyl)ethylamine derivatives and synthesis of thieno(3,2-C)pyridine derivatives therefrom | SYNTEX (U.S.A.) INC. (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0439404-A2 | Preparation of 2-(2'-thienyl) alkylamines and derivatives thereof and synthesis of 4,5,6,7- thieno [3,2-c] pyridine derivatives therefrom | SANOFI (FR) | 1991-07-31 | — | — | EP | disclosed |
| US-4997945-A | Ticlopidine intermediate | SYNTEX (U.S.A.) INC. (US) | 1991-03-05 | — | — | US | disclosed |