Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 7/20 | 0.53 |
| ▸ | CTSK | P43235 | 6/20 | 0.53 |
| ▸ | CTSL | P07711 | 3/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.53 |
| ▸ | AKT1 | P31749 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | REN | P00797 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18394929 | 1.00 | ACE (0.54) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL23677933 | 0.96 | IDO1 (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL18396013 | 0.96 | IDO1 (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL23587982 | 0.96 | IDO1 (0.56) | ACECTSSCTSKCTSLCTSB | |
| SCHEMBL29633813 | 0.92 | HDAC3 (0.56) | ACECTSSCTSKCTSLIDO1 | |
| SCHEMBL2837978 | 0.92 | HDAC3 (0.56) | ACECTSSCTSKCTSLIDO1 | |
| SCHEMBL2837981 | 0.92 | HDAC3 (0.56) | ACECTSSCTSKCTSLIDO1 | |
| SCHEMBL3013449 | 0.92 | HDAC3 (0.56) | ACECTSSCTSKCTSLIDO1 | |
| SCHEMBL29809224 | 0.92 | HDAC3 (0.56) | ACECTSSCTSKCTSLIDO1 | |
| SCHEMBL23677827 | 0.91 | IDO1 (0.51) | ACECTSSCTSKCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3613420-B1 | SALTS AND PRODRUGS OF 1-METHYL-D-TRYPTOPHAN | LUMOS PHARMA INC (US) | 2022-05-25 | — | — | EP | disclosed |