Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928405 | 0.85 | KMT2A (0.58) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL1883486 | 0.85 | GAA (0.60) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL24445723 | 0.85 | GAA (0.63) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL6744201 | 0.83 | KMT2A (0.69) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL23269311 | 0.82 | KMT2A (0.58) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL2558736 | 0.81 | SMN1; SMN2 (0.61) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL697566 | 0.81 | SMN1; SMN2 (0.73) | KMT2ATSHRGAAMAPTALDH1A1 | |
| SCHEMBL21625227 | 0.81 | ALDH1A1 (0.64) | KMT2ATSHRMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16384063 | 0.78 | ALDH1A1 (0.65) | TSHRALDH1A1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL4933383 | 0.78 | SMN1; SMN2 (0.57) | KMT2ATSHRGAAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4000609-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING BONE DISEASES | Industry Foundation of Chonnam National University (KR) | 2022-05-25 | — | — | EP | disclosed |