Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.46 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | ESRRA | P11474 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30440431 | 0.85 | KIF11 (0.51) | KIF11HSD17B1PKMAKR1C3AKR1C2 | |
| SCHEMBL840795 | 0.85 | KIF11 (0.51) | KIF11HSD17B1PKMAKR1C3AKR1C2 | |
| SCHEMBL1925084 | 0.84 | KIF11 (0.59) | KIF11PKMAKR1C3AKR1C2HTT | |
| SCHEMBL30669213 | 0.82 | POLB (0.57) | HSD17B1HTTPOLBMAPTMEN1 | |
| SCHEMBL1853155 | 0.82 | ESRRA (0.54) | KIF11HSD17B1PKMHTTESRRA | |
| SCHEMBL850916 | 0.82 | POLB (0.57) | HSD17B1HTTPOLBMAPTMEN1 | |
| SCHEMBL313169 | 0.81 | KIF11 (0.75) | KIF11AKR1C3AKR1C2NOTUMMAOA | |
| SCHEMBL312657 | 0.81 | KIF11 (0.56) | KIF11HSD17B1PKMAKR1C3AKR1C2 | |
| SCHEMBL16838797 | 0.80 | KIF11 (0.51) | KIF11AKR1C3AKR1C2HTTNOTUM | |
| SCHEMBL3902096 | 0.80 | NOTUM (0.69) | HSD17B1HTTNOTUMPDK2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001336-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |