Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2451790 | 0.88 | — | — | |
| SCHEMBL3396955 | 0.82 | NCF1 (0.35) | NCF1CYP2D6RPS6KB1 | |
| SCHEMBL12233405 | 0.74 | — | — | |
| SCHEMBL1010140 | 0.74 | — | — | |
| SCHEMBL861740 | 0.74 | — | — | |
| SCHEMBL3399438 | 0.71 | — | — | |
| SCHEMBL11610360 | 0.70 | — | — | |
| SCHEMBL5900697 | 0.69 | NCF1 (0.40) | NCF1CYP2D6 | |
| SCHEMBL3675984 | 0.69 | TSHR (0.40) | NCF1 | |
| SCHEMBL954911 | 0.69 | TSHR (0.44) | NCF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012961-B2 | Tricyclic antibiotics | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-09-06 | — | — | US | disclosed |