Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | BPTF | Q12830 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1075678 | 0.86 | — | — | |
| SCHEMBL771773 | 0.81 | BCHE (0.39) | CHRM5ADRA2CCYP2D6CARM1PRMT6 | |
| SCHEMBL5900697 | 0.81 | NCF1 (0.40) | NCF1CHRM5ADRA2CKDM4ECYP2D6 | |
| SCHEMBL772031 | 0.81 | BCHE (0.39) | CHRM5ADRA2CCYP2D6CARM1PRMT6 | |
| SCHEMBL772107 | 0.81 | BCHE (0.39) | CHRM5ADRA2CCYP2D6CARM1PRMT6 | |
| SCHEMBL772309 | 0.81 | CYP2D6 (0.47) | CHRM5ADRA2CCYP2D6 | |
| SCHEMBL4580897 | 0.79 | CHRM5 (0.59) | CHRM5ADRA2CKDM4E | |
| Hydrochloric Acid SCHEMBL5793575 | 0.79 | CHRM5 (0.48) | CHRM5ADRA2C | |
| SCHEMBL4579271 | 0.79 | CHRM5 (0.59) | CHRM5ADRA2CKDM4E | |
| SCHEMBL772733 | 0.78 | CYP2D6 (0.36) | CHRM5ADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012961-B2 | Tricyclic antibiotics | ACTELION PHARMACEUTICAL LTD. (CH) | 2011-09-06 | — | — | US | disclosed |