Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.40 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.40 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.36 |
| ▸ | MLYCD | O95822 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18275139 | 0.86 | TSHR (0.44) | CA2KCNJ11SMN1; SMN2ABCC9ABCC8 | |
| SCHEMBL5368194 | 0.84 | KIF11 (0.45) | KIF11CA2CYP2A6HDAC6PDK2 | |
| SCHEMBL312657 | 0.84 | KIF11 (0.56) | KIF11CA2CYP2A6HDAC6PDK2 | |
| SCHEMBL19289366 | 0.80 | CYP2A6 (0.43) | KIF11SMN1; SMN2CYP2A6NPC1MAPT | |
| SCHEMBL12251367 | 0.78 | ESRRA (0.46) | KIF11SMN1; SMN2CYP2A6NPC1MAPT | |
| SCHEMBL1333739 | 0.76 | SMN1; SMN2 (0.61) | CA2KCNJ11SMN1; SMN2ABCC9ABCC8 | |
| SCHEMBL24719100 | 0.76 | MEN1 (0.58) | SMN1; SMN2ARMLYCD | |
| SCHEMBL17287089 | 0.74 | KCNJ11 (0.49) | KCNJ11SMN1; SMN2ABCC9ABCC8KCNJ8 | |
| SCHEMBL313001 | 0.73 | KIF11 (0.51) | KIF11SMN1; SMN2CYP2A6PDK2NPC1 | |
| SCHEMBL13974845 | 0.73 | SMN1; SMN2 (0.44) | KCNJ11SMN1; SMN2ABCC9ABCC8KCNJ8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001336-A1 | POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-05-25 | — | — | EP | disclosed |