SCHEMBL24445906

SCHEMBL24445906

COC(=O)c1c(F)c(O)cc(F)c1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 7/20 0.48
CA2 P00918 7/20 0.48
CA12 O43570 5/20 0.48
CA7 P43166 5/20 0.48
CA9 Q16790 5/20 0.48
CA14 Q9ULX7 5/20 0.48
LMNA P02545 3/20 0.47
XDH P47989 2/20 0.47
GAA P10253 2/20 0.47
KDM4E B2RXH2 2/20 0.47
POLB P06746 1/20 0.47
NFKB1 P19838 1/20 0.47
GFER P55789 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
FUT7 Q11130 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP3A4 P08684 2/20 0.46
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522223 0.88 CA1 (0.52) CA1CA2CA12CA7CA9
SCHEMBL24436890 0.86 CYP3A4 (0.52) CA1CA2CA12CA7CA9
SCHEMBL24436891 0.85 CA12 (0.48) CA1CA2CA12CA7CA9
SCHEMBL29562023 0.79 TSHR (0.41) CA1CA2CA12CA7CA9
SCHEMBL22832001 0.79 TSHR (0.41) CA1CA2CA12CA7CA9
SCHEMBL24436954 0.78 CYP3A4 (0.46) CA1CA2CA9POLBL3MBTL1
SCHEMBL1998427 0.78 MAPT (0.47) CA1CA2CA12CA7CA9
SCHEMBL24445910 0.77 XDH (0.47) CA1CA2CA12CA7CA9
SCHEMBL2472378 0.77 CA12 (0.53) CA1CA2CA12CA7CA9
SCHEMBL19478316 0.77 CA1 (0.45) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4001336-A1 POLYURETHANE, POLYURETHANE PRODUCTION METHOD, CONDUCTIVE PASTE COMPOSITION, CONDUCTIVE WIRE, AND METHOD FOR PRODUCING CONDUCTIVE WIRE Shin-Etsu Chemical Co., Ltd. (JP) 2022-05-25 EP disclosed