Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.56 |
| ▸ | CMA1 | P23946 | 17/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CTRC | Q99895 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16706511 | 1.00 | F2 (0.56) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL28394567 | 1.00 | F2 (0.56) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL16706524 | 0.95 | F2 (0.52) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL23863946 | 0.95 | F2 (0.52) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL24448317 | 0.95 | F2 (0.52) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL23863881 | 0.92 | CMA1 (0.48) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL16706532 | 0.92 | CMA1 (0.48) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL28388489 | 0.92 | CMA1 (0.48) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL28392404 | 0.91 | F2 (0.47) | F2PRSS1CMA1ACECTRC | |
| SCHEMBL18103316 | 0.91 | F2 (0.47) | F2PRSS1CMA1ACECTRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001272-A1 | NMDA ANTAGONIST PRODRUGS | Astrazeneca AB (SE) | 2022-05-25 | — | — | EP | disclosed |