Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 7/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.43 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.43 |
| ▸ | F2R | P25116 | 2/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24447417 | 0.87 | YAP1 (0.43) | MEN1MAPTKMT2AGAAGFER | |
| SCHEMBL24448520 | 0.85 | PREP (0.45) | DPP4DPP8DPP7 | |
| SCHEMBL24448514 | 0.85 | DPP4 (0.40) | MEN1MAPTKMT2AGAAGFER | |
| SCHEMBL24448185 | 0.85 | DPP4 (0.39) | MEN1MAPTKMT2AGAAGFER | |
| SCHEMBL24447064 | 0.84 | DPP4 (0.46) | DPP4YAP1TEAD4DPP8DPP7 | |
| SCHEMBL24932678 | 0.84 | PREP (0.45) | DPP4DPP8DPP7 | |
| SCHEMBL24446735 | 0.84 | DPP4 (0.40) | MEN1MAPTKMT2AGAAGFER | |
| SCHEMBL24932568 | 0.84 | DPP4 (0.44) | MEN1MAPTKMT2AGAAGFER | |
| SCHEMBL25473095 | 0.83 | DPP4 (0.45) | MEN1MAPTKMT2AGAAGFER | |
| SCHEMBL24447985 | 0.81 | DPP4 (0.45) | MEN1KMT2ADPP4DPP8DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001279-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |