Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | PRMT3 | O60678 | 5/20 | 0.40 |
| ▸ | DPP4 | P27487 | 4/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24448520 | 0.91 | PREP (0.45) | PREPDPP4DPP8DPP7 | |
| SCHEMBL24448169 | 0.88 | PREP (0.43) | NPC1RAB9APREPDPP4DPP8 | |
| SCHEMBL24447985 | 0.83 | DPP4 (0.45) | PREPDPP4DPP8DPP7 | |
| SCHEMBL24932678 | 0.82 | PREP (0.45) | PREPDPP4DPP8DPP7 | |
| SCHEMBL24447487 | 0.82 | PREP (0.44) | PREPDPP4DPP8DPP7DPP9 | |
| SCHEMBL24447121 | 0.80 | EPHX1 (0.47) | NPC1RAB9APREPEPHX1DPP4 | |
| SCHEMBL24932568 | 0.80 | DPP4 (0.44) | MAPTPREPDPP4DPP8DPP7 | |
| SCHEMBL11377789 | 0.80 | DPP4 (0.50) | PREPEPHX1DPP4DPP8DPP7 | |
| SCHEMBL24447064 | 0.78 | DPP4 (0.46) | PREPDPP4DPP8DPP7DPP9 | |
| SCHEMBL24447476 | 0.78 | MEN1 (0.44) | NPC1MAPTRAB9ADPP4DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4001279-A1 | NOVEL SPIROPYRROLIDINE DERIVED ANTIVIRAL AGENTS | Enanta Pharmaceuticals, Inc. (US) | 2022-05-25 | — | — | EP | disclosed |