⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21316497 | 0.60 | — | — | |
| SCHEMBL24449835 | 0.60 | — | — | |
| SCHEMBL24449412 | 0.60 | — | — | |
| SCHEMBL18997578 | 0.57 | — | — | |
| SCHEMBL25453685 | 0.55 | — | — | |
| SCHEMBL24449415 | 0.55 | — | — | |
| SCHEMBL9891493 | 0.54 | — | — | |
| SCHEMBL22454130 | 0.54 | RIPK1 (0.31) | — | |
| SCHEMBL22433361 | 0.52 | — | — | |
| SCHEMBL22861258 | 0.51 | PHGDH (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220162197-A1 | MYST FAMILY HISTONE ACETYLTRANSFERASE INHIBITORS | Epizyme, Inc. | 2022-05-26 | — | — | US | disclosed |