Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 8/20 | 0.75 |
| ▸ | ABL2 | P42684 | 6/20 | 0.75 |
| ▸ | KIT | P10721 | 4/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.50 |
| ▸ | FLT3 | P36888 | 2/20 | 0.47 |
| ▸ | CSF1R | P07333 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 3/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19317676 | 0.86 | ABL1 (1.00) | ABL1ABL2KITMAPK14CDK2 | |
| SCHEMBL19317711 | 0.82 | ABL1 (0.53) | ABL1ABL2KITMAPK14FLT3 | |
| SCHEMBL19317706 | 0.80 | ABL1 (0.76) | ABL1ABL2MAPK14FLT3CSF1R | |
| SCHEMBL19317694 | 0.80 | ABL1 (0.89) | ABL1ABL2KITMAPK14FLT3 | |
| SCHEMBL19317696 | 0.80 | ABL1 (0.89) | ABL1ABL2KITMAPK14CDK2 | |
| SCHEMBL19317697 | 0.78 | ABL1 (0.86) | ABL1ABL2KITMAPK14 | |
| SCHEMBL19317699 | 0.78 | ABL1 (0.86) | ABL1ABL2KITMAPK14CDK2 | |
| SCHEMBL19317690 | 0.76 | ABL1 (0.83) | ABL1ABL2KITMAPK14CDK2 | |
| SCHEMBL19317688 | 0.75 | ABL1 (0.81) | ABL1ABL2KITMAPK14 | |
| SCHEMBL19317692 | 0.75 | ABL1 (0.64) | ABL1ABL2KITMAPK14FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | CORNELL UNIVERSITY | 2022-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220160705-A1 | METHODS FOR CONTROLLING PROSTAGLANDIN-MEDIATED BIOLOGICAL PROCESSES | PTGES, PTGS1, PTGES2 | ABL1 4516/4885ABL2 2755/4885KIT 2155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.