SCHEMBL2445199

SCHEMBL2445199

Cc1cc(C2(c3ccc(Oc4ccc(C(F)(F)F)c(N)c4)c(C)c3)c3ccccc3-c3ccccc32)ccc1Oc1ccc(C(F)(F)F)c(N)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
ESR2 Q92731 1/20 0.43
AR P10275 11/20 0.40
MAPT P10636 3/20 0.37
LMNA P02545 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MEN1 O00255 1/20 0.37
OPRK1 P41145 1/20 0.37
KMT2A Q03164 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
PDK2 Q15119 3/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
NPSR1 Q6W5P4 1/20 0.34
RAB9A P51151 1/20 0.33
ESRRA P11474 1/20 0.32
ATM Q13315 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2443588 0.90 ESR1 (0.44) ESR1ESR2ARMAPTLMNA
SCHEMBL2441859 0.86 ESR1 (0.49) ESR1ESR2ARMAPTLMNA
SCHEMBL25269471 0.86 AR (0.45) ESR1ESR2ARMAPTLMNA
SCHEMBL29418329 0.86 AR (0.45) ESR1ESR2ARMAPTLMNA
SCHEMBL5476258 0.83 ESR1 (0.49) ESR1ESR2ARMAPTLMNA
SCHEMBL2448288 0.83 ESR1 (0.44) ESR1ESR2ARMAPTLMNA
SCHEMBL16429279 0.83 ESR1 (0.59) ESR1ESR2MAPTLMNAKDM4E
SCHEMBL2442461 0.82 ESR1 (0.43) ESR1ESR2ARMAPTLMNA
SCHEMBL2442091 0.82 ESR1 (0.45) ESR1ESR2ARMAPTLMNA
SCHEMBL2445421 0.82 ESR1 (0.45) ESR1ESR2ARMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680140-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2023-06-20 US disclosed
US-20220064379-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-03-03 US disclosed
EP-2128193-B1 POROUS POLYIMIDE IBIDEN CO LTD (JP) 2013-06-19 EP disclosed
US-8022110-B2 Porous polyimide IBIDEN CO., LTD. (JP) 2011-09-20 US disclosed
US-20100048745-A1 POROUS POLYIMIDE IBIDEN CO., LTD (JP) 2010-02-25 US disclosed
EP-2128193-A1 POROUS POLYIMIDE Ibiden Co., Ltd. (JP) 2009-12-02 EP disclosed