Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2441859 | 0.90 | ESR1 (0.49) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL16429104 | 0.89 | ESR1 (0.56) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL5470015 | 0.88 | ESR1 (0.42) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL2444922 | 0.87 | SMN1; SMN2 (0.55) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL2450327 | 0.87 | SMN1; SMN2 (0.50) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL16429279 | 0.86 | ESR1 (0.59) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL2442091 | 0.85 | ESR1 (0.45) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL29579448 | 0.85 | ESR1 (0.65) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL283244 | 0.85 | ESR1 (0.65) | ESR1ESR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL29412612 | 0.85 | ESR1 (0.65) | ESR1ESR2MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070255075-A1 | Aromatic Diamine And Method For Manufacturing Same | JFE CHEMICAL CORPORATION (JP) | 2007-11-01 | — | — | US | disclosed |
| EP-1803705-A1 | AROMATIC DIAMINE AND PROCESS FOR PRODUCING THE SAME | JFE Chemical Corporation (JP) | 2007-07-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070255075-A1 | Aromatic Diamine And Method For Manufacturing Same | AOC1, DDC, PADI1 | ESR1 1381/4885ESR2 2044/4885MAPT 1772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.