SCHEMBL24453022

SCHEMBL24453022

O=S(=O)(CCc1ccc(OCC2CO2)cc1)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
PKM P14618 2/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
TP53 P04637 3/20 0.43
TSHR P16473 3/20 0.43
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
MAPT P10636 2/20 0.43
HPGD P15428 2/20 0.43
HIF1A Q16665 2/20 0.43
CYP1A2 P05177 1/20 0.43
PPARG P37231 1/20 0.43
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.36
PTPRZ1 P23471 1/20 0.35
PTGES2 Q9H7Z7 1/20 0.34
DRD4 P21917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24452770 0.89 ALDH1A1 (0.52) ALDH1A1PKMLMNAGAATP53
SCHEMBL24453013 0.86 ALDH1A1 (0.49) ALDH1A1PKMLMNAGAATP53
SCHEMBL24465359 0.83 ALDH1A1 (0.46) ALDH1A1PKMLMNAGAATP53
SCHEMBL24453054 0.80 ALDH1A1 (0.54) ALDH1A1PKMLMNAGAATP53
SCHEMBL24465352 0.79 ALDH1A1 (0.51) ALDH1A1PKMLMNAGAATP53
SCHEMBL24465420 0.77 ALDH1A1 (0.47) ALDH1A1PKMLMNAGAATP53
SCHEMBL24465393 0.76 ALDH1A1 (0.49) ALDH1A1PKMLMNAGAATP53
SCHEMBL24465351 0.75 ALDH1A1 (0.42) ALDH1A1PKMLMNAGAATP53
SCHEMBL3871705 0.74 TDP1 (0.66) ALDH1A1PKMLMNAGAATP53
SCHEMBL24465350 0.71 ALDH1A1 (0.59) ALDH1A1PKMLMNAGAATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220160281-A1 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-26 US disclosed