SCHEMBL24453069

SCHEMBL24453069

O=C(OC(CS(=O)(=O)O)(C(F)(F)F)C(F)(F)F)c1cccc(OCC2CO2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
TP53 P04637 3/20 0.47
TSHR P16473 3/20 0.47
HIF1A Q16665 2/20 0.47
CYP3A4 P08684 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.39
PKM P14618 2/20 0.38
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
SCN3A Q9NY46 1/20 0.36
KAT6A Q92794 2/20 0.36
NR4A2 P43354 1/20 0.35
NR1H4 Q96RI1 1/20 0.35
MAOB P27338 1/20 0.34
KMT2A Q03164 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 2/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24453071 0.89 ALDH1A1 (0.40) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL24452536 0.87 ALDH1A1 (0.47) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL24453072 0.87 ALDH1A1 (0.39) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL24453064 0.84 ALDH1A1 (0.46) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL24453034 0.82 ALDH1A1 (0.39) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL24452782 0.81 PARP1 (0.47) LMNAMAPT
SCHEMBL24453035 0.78 ALDH1A1 (0.40) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL24452523 0.78 ALDH1A1 (0.46) ALDH1A1TP53TSHRHIF1ACYP3A4
SCHEMBL21786209 0.78 MAPT (0.41) ALDH1A1TP53CYP3A4SMN1; SMN2TDP1
SCHEMBL24452977 0.77 ALDH1A1 (0.52) ALDH1A1TP53TSHRHIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220160281-A1 BIO-ELECTRODE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING BIO-ELECTRODE, AND REACTION COMPOSITE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-05-26 US disclosed