Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.77 |
| ▸ | RXRA | P19793 | 2/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29419455 | 1.00 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL27932414 | 0.90 | PRKAA2 (0.73) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL29419156 | 0.87 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL30060873 | 0.87 | PRKAA2 (1.00) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL14753495 | 0.87 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL14749820 | 0.87 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL31546 | 0.87 | PRKAA2 (1.00) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL3709827 | 0.87 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL28803542 | 0.84 | PRKAA2 (0.68) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL9115745 | 0.84 | PRKAA2 (0.72) | PRKAA2RXRANR1I2NR4A2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113651802-B | One-pot preparation method of pitavastatin calcium intermediate | 天地恒一制药股份有限公司 | 2022-03-29 | — | — | CN | claimed |
| CN-113651802-A | One-pot preparation method of pitavastatin calcium intermediate | 天地恒一制药股份有限公司 | 2021-11-16 | — | — | CN | claimed |
| CN-110407818-A | A kind of preparation method of Pitavastatin Calcium intermediate | ANQING ENJU BIO MEDICINE TECH CO LTD | 2019-11-05 | — | — | CN | claimed |
| US-11814355-B2 | Method for synthesizing pitavastatin t-butyl ester | ANHUI QINGYUN PHARMACEUTICAL AND CHEMICAL CO., LTD. (CN) | 2023-11-14 | — | — | US | disclosed |
| CN-116947922-A | Synthesis process of pitavastatin intermediate | 江苏福瑞康泰药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-113651802-B | One-pot preparation method of pitavastatin calcium intermediate | 天地恒一制药股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-113651802-B | One-pot preparation method of pitavastatin calcium intermediate | 天地恒一制药股份有限公司 | 2022-03-29 | — | — | CN | disclosed |
| CN-113651802-A | One-pot preparation method of pitavastatin calcium intermediate | 天地恒一制药股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-113651802-A | One-pot preparation method of pitavastatin calcium intermediate | 天地恒一制药股份有限公司 | 2021-11-16 | — | — | CN | disclosed |
| CN-108822090-B | Preparation method of statin drug intermediate | 杭州乐敦科技有限公司 | 2020-11-17 | — | — | CN | disclosed |
| CN-110407818-A | A kind of preparation method of Pitavastatin Calcium intermediate | ANQING ENJU BIO MEDICINE TECH CO LTD | 2019-11-05 | — | — | CN | disclosed |
| US-20090275752-A1 | Novel Process for Statins and its Pharmaceutically Acceptable Salts Thereof | MSN LABORATORIES LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
| US-20090275752-A1 | Novel Process for Statins and its Pharmaceutically Acceptable Salts Thereof | MSN LABORATORIES LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
| US-20090275752-A1 | Novel Process for Statins and its Pharmaceutically Acceptable Salts Thereof | MSN LABORATORIES LIMITED (IN) | 2009-11-05 | — | — | US | disclosed |
| EP-1631533-B1 | NOVEL PROCESS FOR STEREOSELECTIVE REDUCTION OF BETA-KETOESTERS | BIOCON LTD (IN) | 2009-03-11 | — | — | EP | disclosed |
| EP-2024341-A2 | NOVEL PROCESS FOR STATINS AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | Satynarayana Reddy, Manne (IN) | 2009-02-18 | — | — | EP | disclosed |
| WO-2007132482-A2 | NOVEL PROCESS FOR THE PREPARATION OF PITAVASTATIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007132482-A2 | NOVEL PROCESS FOR THE PREPARATION OF PITAVASTATIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2007-11-22 | — | — | WO | disclosed |
| WO-2007125547-A2 | NOVEL PROCESS FOR STATINS AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF | SATYANARAYANA REDDY MANNE (IN) | 2007-11-08 | — | — | WO | disclosed |
| WO-1995011898-A1 | CONDENSED PYRIDINE TYPE MEVALONOLACTONE INTERMEDIATE AND PROCESS FOR ITS PRODUCTION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11814355-B2 | Method for synthesizing pitavastatin t-butyl ester | SSTR4, DPP4, VIP | PRKAA2 234/4885RXRA 1209/4885NR1I2 4055/4885 |
| US-20090275752-A1 | Novel Process for Statins and its Pharmaceutically Acceptable Salts Thereof | HMGCR, NPC1L1, PCSK9 | PRKAA2 1726/4885RXRA 1958/4885NR1I2 437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.