Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKAA2 | P54646 | 1/20 | 0.72 |
| ▸ | RXRA | P19793 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | HMGCR | P04035 | 2/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14749820 | 0.84 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL30060873 | 0.84 | PRKAA2 (1.00) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL29419455 | 0.84 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL24454 | 0.84 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL3709827 | 0.84 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL29419156 | 0.84 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL31546 | 0.84 | PRKAA2 (1.00) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL14753495 | 0.84 | PRKAA2 (0.77) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL9115766 | 0.83 | PRKAA2 (0.72) | PRKAA2RXRANR1I2NR4A2PDE4D | |
| SCHEMBL27936537 | 0.83 | PRKAA2 (0.76) | PRKAA2RXRANR1I2NR4A2PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995011898-A1 | CONDENSED PYRIDINE TYPE MEVALONOLACTONE INTERMEDIATE AND PROCESS FOR ITS PRODUCTION | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1995-05-04 | — | — | WO | disclosed |