SCHEMBL2445482

SCHEMBL2445482

CC(=S)C(=O)OC(=O)C(C)=S

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 2/20 0.33
HSD17B10 Q99714 1/20 0.33
LMNA P02545 1/20 0.33
THPO P40225 1/20 0.31
FFAR3 O14843 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
TAS2R38 P59533 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4124058 0.76
SCHEMBL274320 0.69 ALDH1A1 (0.47) ALDH1A1TSHRTDP1HSD17B10LMNA
SCHEMBL677370 0.68
SCHEMBL10585514 0.67 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10LMNA
SCHEMBL3635705 0.67 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10LMNA
SCHEMBL4946539 0.67 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10LMNA
SCHEMBL27977158 0.67 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10LMNA
SCHEMBL21985977 0.65 ALDH1A1 (0.35) ALDH1A1TSHR
SCHEMBL2037090 0.65
SCHEMBL15963 0.64 ALDH1A1 (0.61) ALDH1A1TSHRTDP1HSD17B10LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2550307-B1 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF Henkel IP & Holding GmbH (DE) 2017-11-22 EP disclosed
US-8748503-B2 Macro-photoinitiators and curable compositions thereof Henkel US IP LLC (US) 2014-06-10 US disclosed
EP-2550307-A2 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF Henkel Corporation (US) 2013-01-30 EP disclosed
US-20130018122-A1 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF HENKEL CORPORATION (US) 2013-01-17 US disclosed
WO-2011119272-A2 MACRO-PHOTOINITIATORS AND CURABLE COMPOSITIONS THEREOF HENKEL CORPORATION (US) 2011-09-29 WO disclosed